Page 71 - Revista 2019

Ancestría y cáncer colorrectal en Colombia. Criollo et al

81(3):559-75.
24. R Core Team. (2014) R: A Language and Environment for Statistical Computing. Vienna, Austria: R
Foundation for Statistical Computing.
25. Price AL, Zaitlen NA, Reich D, Patterson N. (2010) New approaches to population stratifi cation in
genome-wide association studies. Nat rev Genet. 11(7):459-63.
26. Guan Y. (2014) Detecting Structure of Haplotypes and Local Ancestry. Genetics. 196(3): 625-642.
27. Bohórquez M, Sahasrabudhe R, Criollo A, Sanabria-Salas MC, Vélez A, Castro JM, et al. (2016) Clini-
cal manifestations of colorectal cancer patients from a large multicenter study in Colombia. Medicine.
95(40): e4883.
28. Risch N, Merikangas k. (1999) The Future of Genetic Studies of Complex Human Diseases. Science.
273:1516-7.
29. Perdue DG, Haverkamp D, Perkins C, Daley CM, Provost E. (2014) Geographic variation in colo-
rectalcancer incidence and mortality, age of onset, and stage at diagnosis among american indian and
Alaska native people, 1990–2009. Am J Public Health. 104(Suppl 3): S404-S14.
30. Webster PC. (2012) Health in Colombia: a system in crisis. Can Med Assoc J. 184(6): E289-E90.
31. Moore SP, Forman D, Piñeros M, Fernández SM, Oliveira Santos M, Bray F. (2014) Cancer in indige-
nous people in Latin America and the Caribbean: a review. Cancer Med. 3(1):70-80.
32. Center for Disease Control and Prevention. (2016) Colorectal cancer rates by race and ethnicity: di-
vision of cancer prevention and control, Centers for Disease Control and Prevention. [updated 16-ju-
nio-2016]. Available from: https://http://www.cdc.gov/cancer/colorectal/statistics/race.htm.
33. Cobb N, Paisano RE. (1998) Patterns of cancer mortality among Native Americans. Cancer.
83(11):2377-83.
34. Sandoval-Castaño EA. (2016) Perfi l de Salud de la Población Indígena, y Perfi l de salud de la pobla-
ción indígena, y medición de desigualdades en salud. Colombia 2016. Bogotá: Ministerio de Salud y
Protección Social. Producto desarrollado en el marco del contrato No. 074 de 2016.
35. Fortini BK, Tring S, Plummer SJ, Edlund CK, Moreno V, Bresalier RS, et al. (2014) Multiple functio-
nal risk variants in a SMAD7 enhancer implicate a colorectal cancer risk haplotype. PLoS One. 9(11):
e111914.
36. Study, C. O. G. E. N. T. (2008) Meta-analysis of genome-wide association data identifi es four new
susceptibility loci for colorectal cancer. Nat Genet. 40 (12):1426-35.
37. Chang Y-WE, Marlin JW, Chance TW, Jakobi R. (2006) RhoA mediates cyclooxygenase-2 signaling
to disrupt the formation of adherens junctions and increase cell motility. Cancer Res. 66(24):11700-8.
38. Okamoto H, Yasui K, Zhao C, Arii S, Inazawa J. (2003) PTK2 and EIF3S3 genes may be amplifi cation
targets at 8q23-q24 and are associated with large hepatocellular carcinomas. Hepatology. 38(5):1242-
9.
39. Liu WM, Maraia RJ, Rubin CM, Schmid CW. (1994) Alu transcripts: cytoplasmic localisation and
regulation by DNA methylation. Nucleic Acids Res. 22(6):1087-95.
40. Zhu M, Chen X, Zhang H, Xiao N, Zhu C, He Q, et al. (2011) AluYb8 Insertion in the MUTYH Gene
and risk of early-onset breast and gastric cancers in the Chinese population. Asian Pac J Cancer Prev.
12(6):1451-5.
41. Borun P, De Rosa M, Nedoszytko B, Walkowiak J, Plawski A. (2015) Specifi c Alu elements involved
in a signifi cant percentage of copy number variations of the STK11 gene in patients with Peutz-Jeghers
syndrome. Fam Cancer. 14(3):455-61.
42. Xiao-Jie L, Ai-Mei G, Li-Juan J, Jiang X. (2015) Pseudogene in cancer: real functions and promising
signature. J Med Genet. 52(1):17-24.
43. Lanier MH, McConnell P, Cooper JA. (2016) Cell migration and invadopodia formation require a
membrane-binding domain of CARMIL2. J Biol Chem. 291(3):1076-91.
44. Gieger C, Radhakrishnan A, Cvejic A, Tang W, Porcu E, Pistis G, et al. (2011) New gene functions in
megakaryopoiesis and platelet formation. Nature. 480(7376):201-208.
45. Bai Y, Sun Y, Peng J, Liao H, Gao H, Guo Y, et al. (2014) Overexpression of secretagogin inhibits
cell apoptosis and induces chemoresistance in small cell lung cancer under the regulation of miR-494.
Oncotarget. 5(17):7760-75.

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